Aras Part Medical International Press International Journal of Medical Parasitology and Epidemiology Sciences 2766-6492 5 1 2024 03 29 Cytomegalovirus Primo-Infection, a New Sexually Transmitted Disease? Two Cases Report 31 34 10.34172/ijmpes.3160 EN Vincent Jeantils Patrice Bouree https://orcid.org/0000-0001-9657-2924 Journal Article 10.34172/ijmpes.3160 2023 12 05 2024 03 18 Cytomegalovirus (CMV) is a well-known and ubiquitous virus that causes damage in pregnant women, immunocompromised individuals, and babies in the nursery. It is a direct transmission through biologic liquids, asymptomatic in most cases, sometimes with a mononucleosis-like syndrome. It can be diagnosed using a serologic, or much better, a PCR test. Two cases of primary CMV infections are discussed and linked to probable sexual transmission.