Tesfaye Rebuma
1* 
, Sanaz Mehdipour
21 Shaggar City Administration, Sebeta Sub City Agricultural Office, Sebeta, Oromia, Ethiopia
2 Department of Pathobiology, Faculty of Veterinary Medicine, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran
Abstract
Rabies is among the most neglected tropical diseases. The Lyssavirus genus causes rabies, a deadly zoonotic illness that affects mammals worldwide, including humans. Although pre-exposure and post-exposure prophylaxis (PEP) vaccines are now available, rabies still poses a serious threat to public health, especially in underdeveloped nations. This article looks at the dynamics of rabies transmission, clinical signs, difficulties in diagnosing the disease, and prevention measures. It highlights the vital importance of all-encompassing immunization programs, creative oral vaccination campaigns for wildlife, and joint ventures between the veterinary and medical fields. The World Health Organization’s (WHO’s) global aims for rabies elimination depend on improved surveillance and public education.